Rose: Queen Victoria is a werewolf?
Doctor: Could be. And her family had the Royal disease. Maybe she gave them a quick nip.
Rose: So, the Royal Family are werewolves?
Doctor: Well, maybe not yet. I mean, a single wolf cell could take a hundred years to mature. Might be ready by, ooh.. early 21st century?
Rose: Nah, that’s just ridiculous! Mind you. Princess Anne..
Doctor: I’ll say no more!
Rose: And if you think about it, they’re very private. They plan everything in advance. They could schedule themselves around the moon, we’d never know! They like hunting! They love blood sports! Oh my God, they’re werewolves!
Queen Victoria: Then you can think on this also, that I am not amused.
Rose Tyler: Yes!
Doctor Who - 2.02 “Tooth and Claw”